Using the brain network, 1,846 genes reprioritized from the Jpn cohort are enriched for NP2 neural progenitor cell-enriched genes (OR = 1.64, Q = 4.10E-17) and genes down-regulated in Sdt/Npy-expressing interneurons of HD patients versus controls (OR = 1.62, Q = 2.90E-16) in the HDSigDB Human 2021 (Supplementary Data S10). Here, NPY is linked to Huntington disease.