DM patients with hs-TnT levels ≥5 URL had a significantly higher adjusted HR for ischemic events (HR: 1.91, 95% CI: 1.19–3.09, P = 0.0079, P for interaction = 0.7773) and all-cause death (HR: 2.78, 95% CI: 1.62–4.76, P = 0.0002, P for interaction = 0.0125) (Table 3). The gene discussed is MAP3K14; the disease is diabetes mellitus.