STAT3 and Alzheimer disease: Conversely, STAT3 inhibition has been shown to reduce neuroinflammation, decrease Aβ levels, and improve cognitive function in AD models (Reichenbach et al., 2019; Choi et al., 2020; Ben Haim et al., 2015; Ceyzériat et al., 2018b; Zhou et al., 2024; Mehla et al., 2021).