In this case, laboratory findings during gabapentin therapy-including hypoalbuminemia (25.9-29.5 g/L), hypocalcemia (1.90-2.02 mmol/L), mild hyponatremia (128-133 mEq/L), and elevated prothrombin time (PT)/ international normalized ratio (INR)/ activated partial thromboplastin time (APTT), highlight the need for comprehensive metabolic and coagulation monitoring in medically complex patients treated for refractory hiccups. The gene discussed is F2; the disease is Hypocalcemia.