It has also been reported [8] that in JIA patients, multiple miRNAs, such as miRNA-21 and miRNA-19a, affect the regulation of the JAK/STAT signaling pathway. Xiaoxun Du et al. [9] have shown that miRNA-223 promotes the inflammatory response and induces cell injury of nucleus pulposus cells by acting on the JAK2/STAT1 pathway. Here, SOAT1 is linked to juvenile idiopathic arthritis.