BDNF and early-onset autosomal dominant Alzheimer disease: Key word included are: ("Alzheimer's disease" OR dementia) AND ("viral" OR "non-viral vectors" OR "gene therapy" OR "gene transfer" OR "viral vector" OR "AAV" OR "lentivirus" OR "CRISPR") AND ("Neurotrophic factors" OR "NTF" OR "NGF" OR "nerve growth factor" OR "BDNF" OR "brain-derived neurotrophic factor").