A significant positive correlation between eGFR and GPR-120 levels is shown in Figure 3, suggesting GPR-120's potential as a renal biomarker. As kidney function deteriorates (lower eGFR), GPR-120 concentrations decline, indicating a potential biomarker role for GPR-120 in predicting the progression of DN and associated metabolic-renal dysfunction in high-risk individuals. Here, FFAR4 is linked to liver dysplastic nodule.