STUB1 and cancer: Clonal hematopoiesis of indeterminate potential (CHIP) is a condition that occurs with age as a result of somatic mutations within hematopoietic stem cells, leading to the emergence of somatically mutated blood cell clones [10]. CHIP has also been associated with a high risk of hematologic malignancy as well as cardiovascular disease [10]. The interplay between CHIP and iron overload is an emerging area of interest since both diseases intersect in common pathways that involve oxidative stress and inflammation and may increase the risk of cancer development in aging cohorts [11].