The IC score (immune cell score: IC indicates the percentage of the tumour area that is occupied by PD-L1-positive tumour-infiltrating immune cells, such as lymphocytes, macrophages, granulocytes, dendritic cells) and the TAP (tumour area positive) score can also be considered, albeit they are currently less relevant, as the study situation regarding immune checkpoint blockade is changing rapidly and future approvals are difficult to predict. This evidence concerns the gene CD274 and neoplasm.