For instance, an ABCD1 mutation (c.253dup leading to p.Arg85Profs*110) was detected in 35 patients (out of 96 pedigree members) among an extended pedigree among Lurs, suggesting high prevalence of X-ALD among consanguineous Lurs [23]. This evidence concerns the gene ABCD1 and X-linked adrenoleukodystrophy.