Notably, a significant increase in CD11b intensity was observed when neutrophils were cocultured with NEC organoids and stimulated with LPS compared to unstimulated NEC cocultures (NEC + neutrophils: 20,498 ± 7,112; NEC + LPS + neutrophils: 28,159 ± 4,829; p = 0.0115) (Figure 3E). The gene discussed is ITGAM; the disease is necrotizing enterocolitis.