Following LPS stimulation, neutrophils cocultured with either NEC or CO organoids showed significantly higher CD11b signal intensity than neutrophils in monoculture, regardless of LPS treatment (NEC + LPS + neutrophils: 28,159 ± 4,829; CO + LPS + neutrophils: 25,629 ± 4,431; neutrophils: 13,469 ± 6,267; neutrophils + LPS: 15,144 ± 1,813; p < 0.05). The gene discussed is ITGAM; the disease is necrotizing enterocolitis.