Notably, CD4+ T cells (CD45+ CD3+ γδTCR− NK1.1− CD4+), natural killer T (NKT) cells (CD45+ CD3+ γδTCR−, NK1.1+), tumor-associated neutrophils (TANs; CD45+ CD11b+ CD11c− Ly6Clow Ly6G+ F4/80−) and plasmacytoid dendritic cells (pDCs; CD45+ CD11c+ Ly6G− CD11b− MHC II+ F4/80+ CD317+) were significantly elevated within the TME of DNA-vaccinated mice. This evidence concerns the gene CD4 and neoplasm.