The ASPH inhibitor MO-I-1151 alone did not reduce tumor growth, although we found a high level of the ASPH protein in TC-1/A9 cells and demonstrated the effect of ASPH inhibition on cell proliferation, migration, and invasion in our previous in vitro study.18 In addition, the dosing regimen successfully inhibited tumor growth and metastasis in other tumor models.9, Here, ASPH is linked to neoplasm.