TGFB1 and asthma: Deleterious roles of TGFβ have also been described in the airway during pathological airway remodeling: in asthma (a condition where we observe increased LTBP2 expression) TGFβ has been linked to goblet cell hyperplasia and increased mucosal secretions, subepithelial fibroblast proliferation and fibrosis, smooth muscle cell hyperplasia, and epithelial cell apoptosis36.