This pathway is governed by nicotinamide phosphoribosyltransferase (NAMPT), an enzyme that is overexpressed in diverse malignancies, including neuroendocrine tumors, lymphomas, and adrenocortical carcinomas (Kozako et al., 2019; Sawicka-Gutaj et al., 2022; Nomura et al., 2023). Here, NAMPT is linked to adrenal cortex carcinoma.