Also, there was a moderate agreement between pathologic and radiologic responses regarding postmenopausal patients (Kappa: 0.627, sensitivity: 87.5%, specificity: 78.6%, and accuracy: 81.8%) and patients who had HER2 + type of breast cancer (Kappa: 0.609, sensitivity: 100%, specificity: 87.5%, and accuracy: 88.9%). The gene discussed is ERBB2; the disease is breast carcinoma.