To validate whether LINC00622 regulates autophagy through mTORC1 pathway, we treated melanoma cells with autophagy inhibitor MHY1485 (a potent activator of mTORC1 to inhibit the fusion between autophagosomes and lysosomes) and 3-MA (a PI3K inhibitor widely used to inhibit autophagy). Here, LINC00622 is linked to melanoma.