CRTC1 and melanoma: Gene Ontology (GO) analysis indicated the category list consistently includes “Cellular response to external stimulus”, “response to leucine”, “cellular response to leucine”, “cellular response to leucine starvation”, “positive regulation of TORC1 signaling”, “response to starvation”, “regulation of TORC1 signaling”, “positive regulation of TOR signaling” in melanoma cells (Fig. 3E and Supplementary Table S3).