METTL3 and hepatocellular carcinoma: To assess the role of MCM10 and its correlation with METTL3 in HCC progression, we found that knockdown of MCM10 inhibited the proliferation, invasion, and migration of hepatoma cells, while overexpression of MCM10 rescued the malignant phenotypes in METTL3-deficient cells (Fig. 5K–M; Fig. S6F–H).