FLT4 and lobular neoplasia: Therefore, we investigated the relationship between lymphatic vessel expression and the revised International Society of Nephrology/Renal Pathology Society (ISN/RPS) histopathologic classification of LN and the modified National Institutes of Health (NIH) activity indexes in human LN and the effect of VEGFR-3 inhibition on lymphoid aggregations and lymphatic vessel expression in the resiquimod-induced LN model.