Probiotics such as Lactobacillus rhamnosus, Bifidobacterium bifidum, and Akkermansia muciniphila have demonstrated the ability to reduce NF-κB activation, suppressing the expression of pro-inflammatory cytokines such as TNF-α, IL-6, and IL-1β, which are involved in tumour progression [131]. This evidence concerns the gene NFKB1 and neoplasm.