However, pregnancy-associated fulminant type 1 diabetes is distinguished by significantly lower arterial blood pH, elevated serum amylase levels, and significantly higher prevalence of the HLA-DRB1*09:01-DQB1*03:03 haplotype compared to non-pregnancy-associated fulminant type 1 diabetes [38]. This evidence concerns the gene HLA-DRB1 and type 1 diabetes mellitus.