GDF15 and metabolic dysfunction-associated steatohepatitis: The correlation study with histological features showed that in patients with MASH, the plasma levels of GDF15 exhibited no correlation with steatosis, ballooning, and inflammation, while they were positively correlated with fibrosis (r = 0.48, p = 0.0001), with a significant increase in fibrosis stage 3 (Figure 2B).