From our results, it also emerged, contrarily to Werge et al. [19], that children with MASH and a murine model of diet-induced MASH displayed a significant increase in hepatic GDF15 gene expression, which was consistent with that observed for the key profibrogenic markers COL1A1 and COL3A1. The gene discussed is GDF15; the disease is metabolic dysfunction-associated steatohepatitis.