Galectin 2 (Gal-2) could exert a protective role during allergic inflammation by inducing apoptosis of CD8+ T cells [90], while Gal-3 seems to exacerbate asthma, atopic dermatitis, and EAE by promoting an (Immunoglobulin E) IgE increase [91,92,93]. The gene discussed is LGALS2; the disease is atopic eczema.