CD79A and lymphoma: Key histopathological features linked to disease severity and lymphoma risk include massive B-cell infiltration, ectopic germinal centers (GCs)—linked to genetic instability and malignant transformation; lymphoepithelial lesions (LELs)—characterized by lymphocytic infiltration into glandular ducts with epithelial hyperplasia; and altered ratios of IgA+, IgG+, and IgM+ plasma cells—a reduction in IgA+ cells (below 70%) is highly specific for SjD (sensitivity 100%; specificity 95.4%) [10,11,12].