CAPN5 and neurodevelopmental disorder: Many CAPN5 substrate candidates identified in this study harbor genetic variants that cause human diseases including several neurodevelopmental disorders [32,45,46,47,48,49,50,51,52,53,54,55,56,57,58,59,60,61,62,63,64,65,66,67,68,69,70,71] (Table 2).