Medali and coworkers [22] used left anterior descending coronary artery permanent ligation to create myocardial infarction in mice to test the effects of thioredoxin-1 (Trx-1), Trx-80, and mimetic peptide of Trx-1 (Ac-Cys-Pro-Cys-amide, CB3) on cardiomyocyte apoptosis and cardiac function. Here, TXN is linked to myocardial infarction.