It would be of interest to explore the possibility of decreasing the expression of SCNA, which encodes α-synuclein [108], or increasing the expression of the neuroprotective gene Nrf2, whose product reduces ROS levels in neurons and is thus neuroprotective [109], particularly given that Nrf2 has already been activated in the brains of healthy mice by dCas9-VP64 [110] to combat Parkinson’s disease. This evidence concerns the gene SNCA and Parkinson disease.