CRP and mood disorder: The systematic review and meta-analysis by Miola et al. [58] included 21 studies and 7682 participants with a psychiatric diagnosis (7445 with mood disorders), finding a large association between CRP concentrations and suicidal ideation (SMD 1.145, 95% CI 0.273–2.018), and a medium association with suicide attempts (SMD 0.549, 95% CI 0.363–0.735).