As shown, DNMT3α (Figure 6A) and HD1 (Figure 6B) mRNA levels were significantly upregulated in LEC collected from patients with myopia for DNMT3α (p < 0.05) and high myopia (respectively, p < 0.005 and p < 0.005), as compared to emmetrope. This evidence concerns the gene DNMT3A and myopia.