CALR and AL amyloidosis: Previous research has shown that GABARAP interacts directly with CALR in vitro and it co-localizes (punctuate structure) and co-immunoprecipitates with CALR in the mouse neural precursor and neuroblastoma model N2a (Neuro 2A) cells, as well as in AMO1 multiple myeloma cells, respectively [28,29,30].