IL10 and head and neck squamous cell carcinoma: HNSCC cells also recruit immunosuppressive plasmacytoid DCs (pDCs) via the secretion of C-X-C motif chemokine ligand (CXCL)12 and CXCL14; pDCs secrete IL-10 further recruit more Tregs, dampening the immune attack even more [56,57].