Among others like SIRT1 (Sirtuin 1) deacetylase, AMPK, GATA1 and NRF2 (Nuclear factor erythroid 2-related factor 2), the tumor suppressor gene p53 and the oncogene c-Myc receive special attention as they implicate the role of circadian control in DNA repair and tumor development [30,33,34,35]. This evidence concerns the gene SIRT1 and neoplasm.