We successfully identified five genetic variants that may influence the risk of neuropathy in patients with type 2 diabetes: the rs2032930 and rs2032931 variants in the RecQ-mediated genome instability protein 2 (RMI2) gene and the rs604349 variant in the myosin-binding protein H-like (MYBPHL) gene were found to increase the risk of neuropathy by 22–49-fold, while the rs917778 SNP in the multivesicular body subunit 12B (MVB12B) gene and the rs2234753 SNP in the retinoic acid X receptor alpha (RXRA) gene were found to reduce the probability of neuropathy to 0.07–0.08 [13]. This evidence concerns the gene RMI2 and type 2 diabetes mellitus.