Numerous studies confirm that azurin is able to enter tumor cells and inhibit their growth; this leads to cell shrinkage and death through multiple mechanisms, including (i) binding to the DNA-binding domain (DBD) of the tumor suppressor protein p53, (ii) antiproliferative activity, and (iii) proapoptotic activity [17,32,33,34]. Here, TP53 is linked to neoplasm.