Pathway analysis identified 32 common pathways among KIRC, KIRP, and KICH (kidney chromophobe carcinoma), with several uniquely dysregulated pathways, including calcium signaling, cytokine-cytokine receptor interaction, steroid hormone biosynthesis, cell adhesion molecules (CAMs), and PPAR signaling. The gene discussed is PPARA; the disease is chromophobe renal cell carcinoma.