To further validate the relationship of B. stenostachya and melanoma, the bioactive compounds of the plant were docked with the melanoma related proteins which include the proto-oncogene serine/threonine protein kinase, a mitogen-activated protein kinase, cyclin dependent kinase 2, and phosphoinositide-dependent kinase-1 and were compared with two controls. This evidence concerns the gene WNK2 and melanoma.