In summary, all these examples are only a small sample of reported observations showing the effect of a myriad of antioxidant molecules acting through Nrf2 and that tend to confirm that activators of the Nrf2 pathway induce the production of phase II antioxidative enzymes [89,90,91], protect retinae from destruction and limit inflammation and the occurrence of symptoms similar to those observed during dry AMD in humans. The gene discussed is NFE2L2; the disease is dry age related macular degeneration.