In an animal experiment, DEHP caused a significant reduction in the number of CD8α dendritic cells (DCs) and bone marrow DC progenitors in the spleen of mice by affecting dendritic cell homeostasis, differentiation, and peroxisome proliferator-activated receptor gamma (PPARγ) activity, which ultimately led to allergic asthma [76]. This evidence concerns the gene CD8A and allergic asthma.