The study found a strong correlation between markers of renal injury (CysC and NGAL) and inflammatory mediators (albumin, IL-6, IFN-γ, IL-4, TNF-α, IL-15, and IL-1β), underscoring the impact of CRS involvement on renal injury during SARS-CoV-2 infection. This evidence concerns the gene IL4 and congenital rubella syndrome.