DUOX2 and necrotizing enterocolitis: We found that the NOXO1 (p = 0.0001, −2635–11,670), DUOX2 (p = 0.043, 260–9463), and DUOXA2 (p = 0.0047, 1068–3107) were significantly upregulated in enteroids from patients with NEC compared to control patient enteroids (Figure 4).