Among the identified upregulated genes were the glutamate receptors GRIN1A and gria3a/b and the GABA receptor gabra1, gabrd, and gabrg2 whose both LOF and GOF mutations in human orthologs are known to cause neurodevelopmental phenotypes including epilepsy, cognitive impairment and/or ASD [118,119,120,121,122,123,124]. The gene discussed is GABRA1; the disease is Cognitive impairment.