The transcription factors with probable metabolic correlation with PCa, including AR, are protein 53 kDa (p53), cellular myelocytomatosis protein (c-Myc or MYC), hypoxia-inducible factor 1 (HIF-1), and nuclear factor erythroid 2-related factor 2 (Nrf2). Here, SETD2 is linked to posterior cortical atrophy.