Most recently, the Breast Cancer Association Consortium (BCAC) used a panel of 34 putative susceptibility genes to perform sequencing on samples from 60,466 women with breast cancer and 53,461 controls and identified only 31 carriers of GEN1 truncating mutations among cases and 41 in controls (OR = 0.66, p = 0.18), but the localization of the truncating mutations was not provided [42]. This evidence concerns the gene GEN1 and breast cancer.