AKT1 and neoplasm: M2 TAMs upregulated SGLT1 expression in BC cells via the EGFR/phosphatidylinositol-3-kinase (PI3K)/protein kinase B (AKT) signaling pathway, leading to tamoxifen resistance and accelerating tumor growth both in vitro and in vivo, while the depletion of M2 TAMs induced the opposite effects.