TEAD4 and colorectal carcinoma: These findings suggest TEAD4 may engage in cytoplasmic interactions in TETs, possibly through complex formation, alternative splicing (e.g., TEAD4-S) [31], or cytoplasmic signaling crosstalk, unlike in other tumors such as hepatocellular [1,25] or colorectal carcinomas [19], where TEAD4 functions predominantly in the cell nucleus.