CASP3 and esophageal cancer: As shown in Figure 10c,d, the expression of the Bcl-2 gene that inhibits apoptosis in both esophageal cancer cells significantly decreased (p < 0.05) after CAP treatment, while the expression of Bax, caspase-3, caspase-8, and caspase-9 genes that promote apoptosis significantly increased (p < 0.05), and showed a time-dependent effect.