Zhang et al. [63] reported that APS support CAR-T cell function by promoting the formation and maintenance of CD122+/CXCR3+/PD-1 memory T cell subsets, reducing the frequency of PD-1+ exhausted T cells, and increasing the expression of chemokines, such as CXCL9 and CXCL10, within the tumour microenvironment. The gene discussed is IL2RB; the disease is neoplasm.