For example, eupafolin, derived from Salvia plebeia, was reported to inhibit the proliferation, migration, and invasion of NSCLC cells by modulating FAK/PI3K/Akt signaling and downregulating metastasis-associated markers, such as MMP9 and RhoA [10]; kaempferol derivatives and platanoside from Angelica acutiloba induce pyroptosis in A549 cells through the NF-κB/NLRP3 inflammasome pathway [11]. This evidence concerns the gene PIK3CA and non-small cell lung carcinoma.