GCGR and pancreatic insulinoma: Regarding the expression of the GCGR and GLP-1R in these cases, a significant decrease in intensity staining for the GCGR and GLP-1R was observed in non-functional pNETs compared to normal pancreas tissue (Figure 5D,E), while in insulinomas, pNETs showed high-intensity staining for GLP-1R similar to normal pancreas tissue (Figure 5E).