Moreover, PGG was also isolated from Terminalia chebula fruits, Rhodiola crenulata roots, and Rhus chinensis plant, showing critical biological activities such as AChE-, BChE-, and BACE1-inhibitory effects and anti-inflammatory effects [38,39], suggesting that it can be a potential multitargeting therapeutic agent of AD. The gene discussed is BACE1; the disease is Alzheimer disease.