Elevated levels of inflammatory biomarkers, such as CRP, interleukin-6 (IL-6), and tumor necrosis factor-alpha (TNF-α), have been consistently associated with the occurrence and prognosis of AF, underscoring the role of inflammatory processes in atrial remodeling, fibrosis, and thrombogenesis [27,28]. The gene discussed is TNF; the disease is atrial fibrillation.